Donations made will fund vaccines in middle- and lower-income countries to help combat the pandemic and the Virgin Atlantic Foundation has pledged an additional £50,000.
The money raised will go to an international financing mechanism called Gavi COVAX Advanced Market Commitment (AMC), which buys Covid-19 vaccines and prioritises those who need them the most.
The campaign asks individuals to donate £4, which is the cost of a single vaccine, with the aim to get 50 million people across the world to take part.
Corneel Koster, chief customer and operating officer for the airline, said Covid-19 is something "we must learn to live with".
