Twice-weekly flights to the Turkish holiday hotspot, operating on Tuesdays and Saturdays, will get under way from 22 June.
One-way fares will lead in from £36.99pp.
Wizz has also announced a three-times weekly Luton-Rzeszow route, flying to the Polish city on Mondays, Wednesdays and Fridays from 22 September.
One-way fares for Rzeszow flights will lead in from £17.99pp.
Owain Jones, Wizz Air UK managing director, said: "We continue to plan for the easing of [Covid] restrictions, as we remain committed to providing the UK with affordable, direct flights to exciting destinations.
"Whether it’s relaxing on the beautiful beaches in Antalya or discovering the historical old town in Rzeszow, our low-fare flights offer UK passengers even more choice when deciding on their post-lockdown holiday destination."
