The 200-passenger ship will call into Portsmouth before departing on a 10-day voyage to the Channel Islands, the Isles of Scilly, and Scottish islands.
It will also complete three expedition voyages across the British Isles and Northern Europe, before heading to the Arctic and Greenland for seven more departures.
Passengers onboard will visit the Scottish islands and Icelandic fjords, as well as lesser-known harbours along the Irish coast.
From 26 October 2025, Silver Endeavour will also host guests on Silversea’s Antarctica Fly Cruise sailings, offering travellers the chance to visit the remote continent by flying directly to King George Island.
The brand will also debut the Earth’s most southerly hotel in 2025/2026 Antarctica season, as part of a collaboration with a consortium of Chilean investors.
Named The Cormorant at 55 South, the property is situated at Isla Navarino and will have a capacity of 150 guests.
All rooms will feature wood tones and earthy elements while also offering views of either the forest or Beagle Channel. There will also be a restaurant, bar, lounge and fitness centre.
“The Cormorant at 55 South is a tribute to the rich culture, breathtaking natural beauty and storied history of Puerto Williams, immersing guests in their destination before embarking on their journey to Antarctica,” said Silversea president Bert Hernandez.
“Every aspect of The Cormorant is thoughtfully designed with our guests in mind, ensuring a comfortable and uniquely Silversea experience.
"Each room offers panoramic views of Patagonia, and the hotel creates a deep connection to the local community, providing specially designed experiences that will allow our guests to begin their expeditions sooner than ever, all in uncompromising comfort.”