The line’s Ambience was due to depart on a three-day Festive Market Getaway cruise from Tilbury on Sunday (18 December).
But after annual maintenance works were conducted, an issue with the ship’s onboard lifeboat station was identified, forcing the line to cancel the sailing.
In a statement, Ambassador said: "We have chosen to immediately address this as a precautionary measure and, as such, will not be able to complete the repair and post-repair test in time to successfully operate today’s sailing.