The firm, headed up by former Olympic Holidays chief Clare Tobin, has chartered flights from Condor for the operation, and will offer departures to Larnaca from Manchester, Birmingham and Gatwick.
Its programme will get under way on 31 July, with Biblio offering a "triple-lock" guarantee built around its trust account model, package holiday pledge and price guarantee.
Biblio will offer a wide portfolio of options, ranging from two-star self-catering properties to five-star boutique stays – including both well-known favourites and "new to UK market" properties.
Seven-night value packages start from £349pp, mid value from £545pp and luxury from £729pp.