Rhodes and Venice will take off in the spring, along with new flights to Stansted, Newquay, Bournemouth and Belfast.
Ryanair is also upping frequencies on more than 30 Edinburgh routes, including to Alicante, Barcelona, Brussels, Milan and Shannon.
It claims capacity will be in excess of 25% higher than in summer 2022, running to 4.7 million annual passengers.
To achieve this growth, Ryanair will base an extra aircraft in Edinburgh this summer, growing its fleet in the Scottish capital to 11.
The additional based aircraft will create more than 30 new pilot and cabin crew jobs in Edinburgh, said the budget carrier.
