The increase in demand came following the Biden administration’s confirmation that the country will reopen its borders on 8 November.
The analysis, which was collected between 1 September and 19 October, was based on redirects, which occur when a customer clicks to book an itinerary with an airline or online travel agent (OTA) through Skyscanner and is then directed to the provider’s site to book.
Skyscanner said booking horizons are in the short-term, with most of the demand focused around the Christmas period, in particular the weeks commencing 13 and 20 December.
The top destination for UK travellers looking to book a transatlantic trip is New York, with a 40% share of redirects, followed by Orlando (15%) and Miami (10%).
The company also reported that following the initial announcement in September that the US is to reopen in November, redirects increased by 800% on a day-by-day basis.
It then reportedly saw a 200% uptick from 14 to 15 October following the confirmation of the exact date.
Average passenger numbers are around two for the majority of destinations, but rose to 2.4 for Orlando and Tampa.
Hugh Aitken, vice-president of flights at Skyscanner, said a large proportion of the demand has come from the UK, but also from markets such as Germany, where carriers with the largest amount of capacity and slots are based.
"Booking horizons remain short, with most of the demand for routes to the United States this side of the year, particularly in December," he added.
Aitken said the resumption of transatlantic travel will "provide a vital boost for many airlines" and help "reconnect travellers on both sides of the pond".
"It immediately helps UK airlines who reply on lucrative US routes, and for the US airlines this announcement comes at a good time as domestic demand softens after a strong summer period," Aitken continued.