The event, which helps develop aviation routes, will be held on the island from June 26 to 28 and is expected to attract about 250 delegates from around the world.
Alberto Bernabe, Tenerife tourism minister, said the island was selected as hosts of the event because it is the closest European region to West Africa at 185 miles rom the Moroccan coast.
He added: “We are delighted and very honoured that Tenerife is hosting this prestigious event.
“Routes Africa is an exciting opportunity for us to showcase our island as a business hub to key aviation industry leaders from Africa, Europe, the Americas and the Middle East.”