Flights to Orlando from Heathrow and Manchester will restart on that day, as will the Heathrow-Las Vegas route. Manchester will also regain its New York service on 8 November.
At Manchester, Virgin will restart both services ahead of new entrant Aer Lingus, which commences flights to New York on 1 December and Orlando on 11 December.
Virgin’s services to Orlando will depart daily from both Heathrow and Manchester.
It said: “The route is currently the most booked across Virgin Atlantic’s global portfolio, reaffirming the pent-up demand for families and thrill seekers to enjoy the magic of Florida’s top destination.”