Flights will operate on Tuesdays and Thursdays using an Airbus A330 with tickets going on sale from February 25.
The new service joins those from Gatwick and Manchester to the Caribbean island and is the sixth launched by the airline this year.
Virgin Atlantic chief commercial officer Shai Weiss said: “The Caribbean has always been a core market for Virgin Atlantic and so we’re excited to announce we’re offering more choice to our customers with the option of flying from Heathrow, Gatwick or Manchester direct to Barbados.”
The flight will offer 33 upper class, 48 premium economy and 185 economy seats. Prices lead in at £649 including tax.
