Vehicles have been driven from Dunkirk and Boulogne along the A16 motorway to Calais with protestors under order to “go slow”.
A blockade near the Channel Tunnel is also threatened as locals protest against the French government’s refusal to close the camp, which has become home to an estimated 7,000 migrants.
A protest organiser, David Sagnard, told BBC News 80 lorries and 100 tractors would take part in the demonstration.
The Foreign Office warned of “significant disruption” on roads leading to Calais.
“There may be limited access to the Eurotunnel terminal. Access to Calais port may also be disrupted,” the FCO said.
P&O Ferries said a diversion route had been created for travellers leaving and entering the port of Calais and said it believed its services would operate as normal.
“Rest assured, if you are delayed due to queues on A16 we will put you on our next available sailing and get you on your way without charge,” the ferry firm tweeted.
“We expect delays on the A16 highway so to access port please use link to plan alternative route.”
Rest assured, if you are delayed due to queues on A16 we will put you on our next available sailing and get you on your way without charge.— P&O Ferries Updates (@POferriesupdate) September 5, 2016
Protestors have said the presence of the camp is undermining Calais and believe its growth has led to a rise in threats from criminal gangs and migrants attempting to board their vehicles to enter the UK, BBC News reports.
Farmers have voiced their anger at the destruction of crops as a result of the increase in the camp’s residents.