The airline has added Ovda serving Israeli seaside resort Eilat, Grenoble in France, Verona in Italy and Tromso in Norway.
Seats are on sale now, with fares starting from £26.99 one-way.
Owain Jones, Wizz Air chief corporate officer, said: “Our new winter destinations takes our Luton network to 51 destinations in 25 countries.
“The routes will be welcomed by our UK customers looking for an exciting winter break, whether that’s winter sunshine, mountain sports or experiencing some of the finest sights nature has to offer.
