The carrier said it has reduced its flying programme in the region due to "continuing uncertainty" and instability affecting airspace.
As part of the changes, British Airways has cancelled all flights to and from Amman, Bahrain, Doha, Dubai and Tel Aviv until later this month, while services between Heathrow and Abu Dhabi will remain suspended until later this year.
The airline said it was keeping the situation under constant review and contacting affected customers with alternative options.
British Airways is also operating limited repatriation flights from Muscat to London Heathrow on 11 and 12 March for customers who already hold bookings. The flights are expected to pause after those dates due to "reduced demand", although the airline said the situation will continue to be reviewed.
The news comes as the UK government promised more repatriation flights this week, with more than 100,000 British holidaymakers still stranded in the Middle East.
Other airlines have also adjusted schedules following mass disruption across the region.
Virgin Atlantic
Virgin Atlantic is another airline to take long-term action following airport and airspace closures in Dubai and Riyadh earlier this month. It has suspended its Dubai route for the rest of the winter season, rather than running until its planned end date of 28 March, explaining that the safety conditions required to continue flights "were not met".
The airline added that flights to Riyadh have been paused for the next two weeks and will continue to be reviewed in line with safety guidance.
Qatar Airways
Qatar Airways said its scheduled operations remain temporarily suspended due to the closure of Qatari airspace on 2 March. It plans to resume normal flights once the Qatar Civil Aviation Authority confirms the full reopening of the country’s airspace.
However, the airline intends to run a limited number of flights in the coming days using temporary operating corridors. Planned departures from Doha on 12 and 13 March include services to destinations such as Heathrow, New York, Frankfurt, Madrid, Mumbai, Delhi and Jakarta.
The flights are intended to help passengers affected by the disruption continue their journeys and "reunite with family members", the airline said.
Emirates
Meanwhile, Emirates said it is operating a reduced schedule after parts of regional airspace reopened. A number of services between Dubai and UK airports have been resumed, including Heathrow, Gatwick, Stansted, Manchester, Birmingham, Glasgow and Edinburgh.
However, the airline also warned that passengers transiting in Dubai will only be accepted if their onward flight is operating. Customers have been advised not to travel to the airport unless they hold a confirmed booking.