He will take up the new role on 1 September.
James Mortimer, the current chief financial officer, will take up the role of interim managing director while the company seeks a replacement for Wratten.
“The board is thankful for Clive’s years of service and leadership,” said John McEwan, chairman of the board.
“We understand and support his decision to take on his new role as an exciting next step in his career and are grateful for his many accomplishments whilst at Amber Road.
“We wish him and his family the very best. We had been working with Clive to build a succession plan over the past year, and I am confident that, with James Mortimer and the rest of the executive leadership team, the company will enjoy continued success in the future.”
Wratten joined Amber Road as commercial director before being appointed as chief executive in November 2015. This followed senior roles at Etihad Airways, Gulf Air, HRG and British Airways.
Suzanne Horner, chair of the BTA added: “I’ve known Clive for many years and his commitment to the BTA as a member of the executive committee makes him the ideal person for the job.
“While we are sad to see Adrian go, we are certain Clive will execute the association’s vision superbly and pick up where Adrian’s great work left off.
“I’m looking forward to working with Clive and the other members of the board on delivering the new BTA mission and continuing the great work we’ve already put in place on behalf of our TMC members and their clients, as well as partners and other industry associates.”