The hotel chain offered 15,000 rooms and more than 1,000 meeting spaces to NHS staff, care workers, families and low-risk patients during the Covid-19 crisis.
Best Western Hotel Rembrandt in Weymouth is now being used as a social care base for those who can’t go home but are well enough to leave hospital.
The property will be home to 31 patients and 13 care staff in partnership with Dorset County Council and Abi Live-In Care services.
A second Best Western hotel, the Grange at Oborne, will open on Easter Monday for 12 patients and six care staff.