It also includes 37 three- or four-night trips from seven other UK bases – Belfast, East Midlands, Leeds Bradford, Glasgow, Edinburgh, Newcastle and Stansted.
Birmingham and Manchester flights will operate from 30 September to 22 November, before resuming from 10 February and running through to 25 April.
Meanwhile, 15 trips from the other seven bases will operate between September and November, and the other 22 between February and April.
Jet2 is offering travel over the October and February half-terms, as well as Easter.
The programme will give holidaymakers the opportunity to explore capital Reykjavik, head out in search of the northern lights, visit Iceland’s Golden Circle, sample its geothermal lagoons and spas, and take in the country’s unique landscape.
Both flight-only and package holiday options are available. Deposits on packages are £60pp.
Packages with Jet2CityBreaks include flights with 22kg hold luggage, a guided northern lights tour, airport transfers, and a choice of three- and four-star hotels in Reykjavik.
Optional excursions include the Golden Circle, Blue Lagoon spa and Iceland’s south shore.
Steve Heapy, Jet2.com and Jet2holidays chief executive, said: “With scheduled flights operating from Manchester and Birmingham, in addition to 37 once-in-a-lifetime trips from seven of our other UK bases, independent travel agents can now offer customers great choice and flexibility when it comes to visiting this bucket list destination.
“Iceland is a destination that is rapidly growing in popularity thanks to its huge variety of choice for travellers. Whether it is geothermal spas, geysers, natural parks, the incredible Aurora Borealis or the world’s northernmost capital Reykjavik, this small North Atlantic island is truly unique."
Jet2’s full winter 2021/22 Iceland programme features:
Belfast International
- Two trips, one in September and one in April
Birmingham
- Scheduled services operating every Monday and Thursday from 30 September to 22 November 2021, and from 10 February to 25 April 2022
Edinburgh
- Two trips, one in October and one in April
East Midlands
- Five trips, one in October, one in November and three in March
Glasgow
- Five trips, two in October, two in February and one in March
Leeds Bradford
- Eight trips, one in October, two in November, two in February, one in March and two in April
Manchester
- Scheduled services operating every Monday and Thursday from 30 September to 22 November 2021, and from 10 February to 25 April 2022
Newcastle
- Ten trips, two in October, two in November, three in February, one in March and two in April
Stansted
- Five trips, one in October, one in November and three in March
