The 14 resorts have been specifically set up to allow guests to "enjoy facilities" such as a pool and the beach.
If holidaymakers stay in the "bubbles" for 14 days and provide negative PCR tests, they will be able to travel about the island freely for the rest of their trip.
However, for shorter stays, guests may leave the resort and travel back home earlier.
Nilen Vencadasmy, chairman of Mauritius Tourism Promotion Authority, said: "Mauritius is delighted to be welcoming international visitors with our 14 unique resort bubbles that allow international visitors to enjoy a safe and secure holiday experience.