Its Around the World in 180 Days voyage will visit 33 countries across four continents, calling at 96 ports.
The trip includes three full days cruising in Antarctica, and takes in more than 60 Unesco World Heritage sites.
Oceania Insignia will sail the itinerary, departing San Francisco on 15 January 2023.
"The response to our 2023 around the world voyage clearly illustrates the enthusiasm that experienced travellers have for immersive and memorable travel experiences," said Oceania president and chief executive Bob Binder.
