Its Around the World in 180 Days voyage will visit 33 countries across four continents, calling at 96 ports.
The trip includes three full days cruising in Antarctica, and takes in more than 60 Unesco World Heritage sites.
Oceania Insignia will sail the itinerary, departing San Francisco on 15 January 2023.
"The response to our 2023 around the world voyage clearly illustrates the enthusiasm that experienced travellers have for immersive and memorable travel experiences," said Oceania president and chief executive Bob Binder.
"Despite the challenges the world faces today, travellers are clearly bullish on the future and are embracing these new opportunities to travel the world and create lifelong memories."
Oceania said that while world cruises typically attracted repeat guests, more than a third of all bookings came from first time, "new-to-brand" guests.
The trend coincides with a steady upward trend in bookings from new-to-brand guests, with some booking windows and promotions attracting levels closer to 50%.
Meanwhile, a fifth of all world cruise guests booked on the voyage have opted to extend their voyage to 218 days.
"The quick uptake from our loyal repeat guests and new first-time guests alike underscores the tremendous pent-up demand for immersive, destination-focused cruises," Binder added.
Oceania said it had seen strong demand for its 2022 Europe and North America collection, particularly longer voyages spanning several weeks or months.
"To satisfy demand from consumers and travel advisors who are booking farther out, the line will be opening the full 2022/23 winter collection of itineraries in March and will open the spring, summer and autumn 2023 Europe and North America voyages beginning in September," the line added.
